9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...
NSI-189 is a novel neurogenic nootropic anti-depressant agent that has successfully undergone Phase 1a clinical trials for depression with 41 healthy volunteers, as well finished Phase 1b trials with 26 depressed patients. In vivo healthy mice testing revealed a remarkable 20% increase in hippocampal volume. Indications for neurogenic and antidepressant...
Optimized Extract - Cannabinoid Receptor Modulation/Endocannabinoid Modulation Research CBRM-OX is a Scientifically Engineered Cannabinoid Receptor/Endocannabinoid Modulator (CB1R/CB2R agonist dominant) Extract.~Indications for anxiolytic, analgesic, antidepressant, myorelaxant, antiemetic, neuroprotective, antiepileptic, immunomodulatory,...
Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications: Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research
Isoxazole-9 (ISX-9) is a neurogenic agent that promotes neurogenesis in vivo through the mechanisms of enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts with resultant effects upon enhancing memory and potential antidepressant effects. Indications for neurogenic and antidepressant research.
β-ANDROSTENETRIOL-OA (TLR-108) is an optimized analogue intended for research into optimization of agents toward the goal of an optimized adjunct agent to foster anxiolysis, cortisol reduction, and reduction of stress induced symptomatologies devoid of any adverse effects. Indicated for anxiolytic/stress and anti-obesity research.
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.
Rasagiline is a novel, highly potent, irreversible monamine oxidase B inhibitor (selective), which is related to Selegiline. It has also been observed to exhibit neuroprotective, neurotrophic, and mitochondriaprotective actions. Rasagiline demonstrates an ability to promote increased levels of NGF, GDNF. and BDNF proteins and expression.
Optimized Extract - Analgesic Optimization Research Scientifically Engineered Selective Opioid Receptor Modulation Extract designed and developed for optimized analgesia with superior therapeutic index with markedly lower tolerance and adverse effects as classical opiate analgesics. Research Indications: Analgesic, Antidepressant, Anxiolytic research
Roflumilast is a potent, long-acting, selective PDE4 Inhibitor (PDE4i) displaying anti-inflammatory and cognitive enhancing/nootropic properties. Indications exist for research that applies to many psychoneurodysfunctional conditions as well as nootropic, ADHD/focus, and anti-inflammatory research.