9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...
NSI-189 is a novel neurogenic nootropic anti-depressant agent that has successfully undergone Phase 1a clinical trials for depression with 41 healthy volunteers, as well finished Phase 1b trials with 26 depressed patients. In vivo healthy mice testing revealed a remarkable 20% increase in hippocampal volume. Indications for neurogenic and antidepressant...
Optimized Extract - Cannabinoid Receptor Modulation/Endocannabinoid Modulation Research CBRM-OX is a Scientifically Engineered Cannabinoid Receptor/Endocannabinoid Modulator (CB1R/CB2R agonist dominant) Extract.~Indications for anxiolytic, analgesic, antidepressant, myorelaxant, antiemetic, neuroprotective, antiepileptic, immunomodulatory,...
Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications: Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research
Piracetam Hydrazide - Nootropic Research
Isoxazole-9 (ISX-9) is a neurogenic agent that promotes neurogenesis in vivo through the mechanisms of enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts with resultant effects upon enhancing memory and potential antidepressant effects. Indications for neurogenic and antidepressant research.
β-ANDROSTENETRIOL-OA (TLR-108) is an optimized analogue intended for research into optimization of agents toward the goal of an optimized adjunct agent to foster anxiolysis, cortisol reduction, and reduction of stress induced symptomatologies devoid of any adverse effects. Indicated for anxiolytic/stress and anti-obesity research.
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.
Rasagiline is a novel, highly potent, irreversible monamine oxidase B inhibitor (selective), which is related to Selegiline. It has also been observed to exhibit neuroprotective, neurotrophic, and mitochondriaprotective actions. Rasagiline demonstrates an ability to promote increased levels of NGF, GDNF. and BDNF proteins and expression.
Optimized Extract - Analgesic Optimization Research Scientifically Engineered Selective Opioid Receptor Modulation Extract designed and developed for optimized analgesia with superior therapeutic index with markedly lower tolerance and adverse effects as classical opiate analgesics. Research Indications: Analgesic, Antidepressant, Anxiolytic research
Roflumilast is a potent, long-acting, selective PDE4 Inhibitor (PDE4i) displaying anti-inflammatory and cognitive enhancing/nootropic properties. Indications exist for research that applies to many psychoneurodysfunctional conditions as well as nootropic, ADHD/focus, and anti-inflammatory research.
Optimized Extract - Addiction Cessation Research Scientifically Engineered Proprietary Optimized Extract Formulation Acting Upon Resetting Addiction Targeted Pathways and Counteracting Hyper-Psychoneurodysfunctional States. Indication for anti-addiction, anti-withdrawal, antidepressant, anxiolytic, neurogenic, anti-obesity, mood disorder treatment, and...
Optimized Extract - Optimized Libidogenic Research Scientifically Engineered Selective Melanocortin-4 Receptor (MC4R) Activator Extract Indicated for libido depression, erectile dysfunction, pro-sexual functionality research
Optimized Extract - Anxiolytic Nootropic Research SGAN-OX Scientifically Engineered Sceletium Anxiolytic Nootropic Extract Indications for anxiolytic, nootropic, anti-inflammatory research.
SBZD-OX Guided Scientifically Engineered Selective BZD Modulator Extract Indications for anxiolytic research.
Emoxypine (a.k.a. Mexidol, Mexifin - specifically within its succinate salt form), is an unusually pleiotropic anti-oxidant with structural resemblance to pyridoxine with several research indications. Indications include anxiolytic, nootropic, neuroprotective, antidepressant, anti-hypoxic, and anti-addictive research.
Optimized Analogue - Eugeroic Nootropic Research *** EUGERAFINIL-OA (TLR-203) is a TLR-OA compound intended for research into optimization of agents toward the goal of an optimized eugeroic to best foster the promotion of effects that include enhanced vigilance, wakefulness, energy, and focus.
Optimized Xtract - Anti-Addiction (Smoking Cessation) Research AASC-OX Scientifically Engineered Mu-Opioid Receptor Antagonist Optimized Extract Concurrent Potent Inhibitory Modulation of AChNRs, VMAT, and DAT. Indications for anti-addiction (smoking cessation, stimulant cessation), anxiolytic, antidepressant, and vigilance/focus/ADHD research.
Alsevetin-OA (TLR-6124) is an optimized agent expressing potent alpha7 NAChR partial agonist activity with moderate efficacy and a high therapeutic index, devoid of tolerance inducing effects. Indications for focus/ADHD, nootropic, anti-addiction, analgesic-sparing research.
Noopepteine-OA (TLR-211) is an optimized analogue based off the Noopept dipeptide platform to encompass optimization toward the goal to foster highly enhanced focus, concentration, energy, and cognition. A marked synergy and enhanced therapeutic index and efficacy is demonstrated with classes of PDE inhibitors. Indications for nootropic, ADHD,...
Agomelatine is a melatonergic agonist promoting fairly rapid acting antidepressant effects. It is particularly effective within paradigms of poor sleep quality and circadian rhythm dysregulation; benefit to anxiolytic and stress-response tone. Indications for antidepressant (MDD), anxiolytic, and somnolescent research, as well as potential indications...
Rimonabant is a potent CB1R inverse agonist demonstrating significant anti-obesity and anti-addiction effects, as well as calorie restriction mimetic (CRM) anti-aging capacities. Research Indications: Anti-obesity, Anti-aging, and Anti-addiction (smoking cessation, et al.) research.
Optimized Extract – Mood Elevation Optimization Research -- Indications for analgesic, antidepressant (mood elevation), anxiolytic (SAD) research
Optimized Extract - Optimized Fear Extinction Research HDAC-OX Scientifically Engineered HDAC Class I Inhibitor (HDAC-C1I) Extract Indications for anxiolytic, fear extinction, analgesia, and antidepressant research (potental for anti-aging research).
HTRI-OX Guided Scientifically Engineered Triple Reuptake Inhibitor Optimized Extract Indications for anti-obesity, antidepressant, and anxiolytic research
SODM-OX Serotonergic Oxytocinergic Dopaminergic Modulation Optimized Extract Indications for anxiolytic, pro-social, antidepressant, and focus/ADHD research
HCBT-OX Herbal Cerebrotrophic Optimized Extract - HCBT-OX fosters proliferation and development of neurons, axon (myelination), dendrites, and synapses in the cerebral cortex and hippocampus. Indications for neurogenic, antidepressant, anxiolytic, neuroregenerative (Alzheimer's Disease, et al.) , and anti-nueropsychodysfunction research.
TCRM-OX Thermogenic Caloric Restriction Mimetic Optimized Extract - Indications for anti-obesity and anti-aging research.
CBSA-OX Guided Scientifically Engineered Cannabinoid Receptor-2 (CB2R) Selective Agonist CBSA-OX is a highly potent and selective CB2R agonist (main active: K(i)=89nM). Research Indications: Cannbinergic/CB2R research, Analgesia, Antidepressant, Anti-Cancer, and Anxiolytic research.
SNRB-OX is a proprietary Optimized Xtract Scientifically Engineered Selective NMDA Receptor Subunit 2B (NR2B) Low-Efficacy Weak Partial Agonist with Functional Antagonist activity. Research Indications: antidepressant, anxiolytic, neuroprotectant, neuroregenerative, and congnition enhancement research. Supplied in solution
ENKI-OX Scientifically Engineered Enkephalinase Inhibitor -- Indications for analgesia, antidepressant, anxiolytic research, and anti-addiction research.
HETA-OX is an Optimized Extract High Efficacy Telomerase Activator superior in efficacy to other present agents within telomerase activation capacity and improvement of markers associated with aging. Indications for anti-aging, antidepressant, and anxiolytic research.
DCRM-OX Dual-Acting Calorie Restriction Mimetic Optimized Xtract Indications for anti-obesity and anti-aging, as well as anti-oxidation research
NEUMYO-OA Ultra-Potent Myostatin & GDF11 Direct Inhibitor is an Optimized Antibody that has high efficacy to antagonize GDF11 ('Neurostatin™') and GDF8 (myostatin) to foster highly significant anti-catabolic/anabolic and myotrophic effects upon skeletal muscle. Research Indications: Anabolic/Myotrophic Research, Anti-Cachexic/Anti-catabolic...
PGCL-OA is an analogue of PGCL optimized toward the goal of pursuit of agents with high potency toward bodyfat reduction and muscle hypertrophy. PGCL-OA is an analogue created that extends the half-life five-fold of the parent molecule PGCL enabling maximal positive effects while negating any adverse effects. Indications for myotrophic/anabolic research...
SARM-OX is an Optimized Xtract developed with the goal of creating the cleanest, pure anabolic agent. Indications myotrophic/anabolic/anti-cachexic research and anti-aging research.
YK-11-OA (TLR-1111) Optimized Analogue is a landmark SARM analogue with Optimized selectivity for potent myotrophic pathways and marginal effects on other parameters usually associated with classical myotrophic/anabolic agents. Of specific importance oral bioavailability is extremely high and yields a highly potent agent. Indications for...
HARA-OX is an orally bioavailable Herbal Androgenic Receptor Activator Optimized Xtract with exceptional potency. HARA-OX is non-steroidal, however is a full agonist at the Androgen Receptor (AR) with a potency approximately 2-3x that of methandrostenolone and no demonstrated hepatotoxicity. Indications for myotrophic/anabolic research.
Cycloastragenol 50% from Astragalus membranaceus (Fisch.) Bunge is a superior form of standardized cycloastragenol that as well has within it other beneficial components, and affords a higher bioavailability than extracts of higher purity, such as 90% and 98% extracts. Research indicates synergistic benefits with HETA-OX, an Optimized Xtract...
Fisetin exerts potent neuroprotectant and neurogenic activity via ERK activation and enhancement of proteasome activity, as well as antioxidant pathways. Enhancement of lifespan has been demonstrated in mouse models of Huntington's Disease. Enhancement of long-term memory has been demonstrated via oral administration. Indications for neurogenic,...
TAO-OA, Thyroid Axis Optimizer, is a proprietary blend of optimized taltirelin and protirelin analogues that has been optimized to produce the goal of optimized positive modulation of the thyroid axis. Indications for research related to the areas of antidepressant effects, memory enhancement, cognition enhancement, motor dysfunction enhancement,...
Nicotinamide Adenine Dinucleotide (NAD+) NAD+ demonstrates highly significant elevated blood plasma levels and has capacity to cross the plasmalemma memebrane and penetrate the blood brain barrier when administered via sublingual and intranasal route in animal models. Indications for anti-aging research, neuroprotectant research, metabolic research,...
Neuserone-OA: 5HT1A Ago-Allosteric Modulator Neurogenic First-in-Class 5HT1A Positive Allosteric Modulator/Co-Agonist, Neurogenic & Acetylcholine Releaser Research Indications for antidepressant, anxiolytic, pro-social, memory and cognition, neurogenic, and neuroprotectant research Solution Format: 100mg/ml 5ml/10ml
Ketanserin Tartrate is a potent and selective 5HT2A antagonist. It has demonstrated neurogenic, addiction cessation, sleep enhancement, anxiolytic, and anti=psychotic properties, among others Research Indications: Serotonergic research, Anxiolytic Research, Psychoneurodysfunctional Research, HPPD-related Research.
Acetyl Semax (syn. Ac Sem, N-Acetyl Semax, Semax Acetyl) Analogue of Semax demostrated to have markedly superior pharmacodynamics to the parent compound, an agent that demonstrates capacity to stimulate operative memory and attention. Semax has been hypothesized to regulate neurotrophic factors that impart benefits towards neuronal and glial cells.
Acetyl Epitalon (syn. Acetyl Epithalon, N-Acetyl-Epitalon, Ac Epi) Epitalon has demonstrated in studies to have notable positive efficacy upon telomeres and aging. The acetyl variant, Acetyl Epitalon, provides far superior metabolic stability and pharmacodynamics.
Acetyl Selank (syn. Ac Sel, N-Acetyl Selank, Selank Acetyl) Analogue of Selank demostrating markedly superior pharmacodynamics and potency.