9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...
NSI-189 is a novel neurogenic nootropic anti-depressant agent that has successfully undergone Phase 1a clinical trials for depression with 41 healthy volunteers, as well finished Phase 1b trials with 26 depressed patients. In vivo healthy mice testing revealed a remarkable 20% increase in hippocampal volume. Indications for neurogenic and antidepressant...
Optimized Extract - Cannabinoid Receptor Modulation/Endocannabinoid Modulation Research CBRM-OX is a Scientifically Engineered Cannabinoid Receptor/Endocannabinoid Modulator (CB1R/CB2R agonist dominant) Extract.~Indications for anxiolytic, analgesic, antidepressant, myorelaxant, antiemetic, neuroprotective, antiepileptic, immunomodulatory,...
Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications: Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research
Isoxazole-9 (ISX-9) is a neurogenic agent that promotes neurogenesis in vivo through the mechanisms of enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts with resultant effects upon enhancing memory and potential antidepressant effects. Indications for neurogenic and antidepressant research.
β-ANDROSTENETRIOL-OA (TLR-108) is an optimized analogue intended for research into optimization of agents toward the goal of an optimized adjunct agent to foster anxiolysis, cortisol reduction, and reduction of stress induced symptomatologies devoid of any adverse effects. Indicated for anxiolytic/stress and anti-obesity research.
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.
Rasagiline is a novel, highly potent, irreversible monamine oxidase B inhibitor (selective), which is related to Selegiline. It has also been observed to exhibit neuroprotective, neurotrophic, and mitochondriaprotective actions. Rasagiline demonstrates an ability to promote increased levels of NGF, GDNF. and BDNF proteins and expression.
Optimized Extract - Analgesic Optimization Research Scientifically Engineered Selective Opioid Receptor Modulation Extract designed and developed for optimized analgesia with superior therapeutic index with markedly lower tolerance and adverse effects as classical opiate analgesics. Research Indications: Analgesic, Antidepressant, Anxiolytic research
Roflumilast is a potent, long-acting, selective PDE4 Inhibitor (PDE4i) displaying anti-inflammatory and cognitive enhancing/nootropic properties. Indications exist for research that applies to many psychoneurodysfunctional conditions as well as nootropic, ADHD/focus, and anti-inflammatory research.
Optimized Extract - Addiction Cessation Research Scientifically Engineered Proprietary Optimized Extract Formulation Acting Upon Resetting Addiction Targeted Pathways and Counteracting Hyper-Psychoneurodysfunctional States. Indication for anti-addiction, anti-withdrawal, antidepressant, anxiolytic, neurogenic, anti-obesity, mood disorder treatment, and...
Optimized Extract - Optimized Libidogenic Research Scientifically Engineered Selective Melanocortin-4 Receptor (MC4R) Activator Extract Indicated for libido depression, erectile dysfunction, pro-sexual functionality research
Optimized Extract - Anxiolytic Nootropic Research SGAN-OX Scientifically Engineered Sceletium Anxiolytic Nootropic Extract Indications for anxiolytic, nootropic, anti-inflammatory research.
SBZD-OX Guided Scientifically Engineered Selective BZD Modulator Extract Indications for anxiolytic research.
Spermidine ≥99% (GC) Synonym: 1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane CAS Number 124-20-9 Linear Formula NH2(CH2)3NH(CH2)4NH2 Molecular Weight 145.25 Beilstein/REAXYS Number 1698591 EC Number 204-689-0 MDL number MFCD00008229 PubChem Substance ID 24899529 NACRES NA.32
SkQ1 CAS# 934826-68-3 (plastoquinonyl decyltriphenyl phosphonium, PDTP) SKQ1 is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS)
Baclofen as a full agonist at the GABA-B receptor acts as a centrally-acting anxiolytic and skeletal muscle relaxant. As well, it shows efficacy in treatment of alcohol cessation. Research Indications: GABAergic Research, Anxiolytic Research, Addiction Cessation Research
NSI-189 is a novel neurogenic nootropic anti-depressant agent that has successfully undergone Phase 1a clinical trials for depression with 41 healthy volunteers, as well finished Phase 1b trials with 26 depressed patients. In vivo healthy mice testing revealed a remarkable 20% increase in hippocampal volume. Indications for neurogenic and antidepressant...
Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications: Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research
J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...
9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
Optimized Analogue - Eugeroic Nootropic Research *** EUGERAFINIL-OA (TLR-203) is a TLR-OA compound intended for research into optimization of agents toward the goal of an optimized eugeroic to best foster the promotion of effects that include enhanced vigilance, wakefulness, energy, and focus.
SENOLYTIXTM is an optimized combination of Dasatinib(D) and Quercetin(Q) based off the landmark science into practically applicable senolytics. SENOLYTIXTM offers the most optimized formulation for progressive research into the paradigm of senolytic agents to date and to afford progress within research against the ravages of aging. Research Indications:...
Emoxypine (a.k.a. Mexidol, Mexifin - specifically within its succinate salt form), is an unusually pleiotropic anti-oxidant with structural resemblance to pyridoxine with several research indications. Indications include anxiolytic, nootropic, neuroprotective, antidepressant, anti-hypoxic, and anti-addictive research.
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.