• 9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications:  Dopaminergic Research, Addiction Research, Neuroprotection Research

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  • J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...

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    $55.30 $79.00 -30%

    Optimized Extract - Cannabinoid Receptor Modulation/Endocannabinoid Modulation Research CBRM-OX is a Scientifically Engineered Cannabinoid Receptor/Endocannabinoid Modulator (CB1R/CB2R agonist dominant) Extract.~Indications for anxiolytic, analgesic, antidepressant, myorelaxant, antiemetic, neuroprotective, antiepileptic, immunomodulatory,...

    $55.30 $79.00 -30%
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  • Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications:  Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research

    $19.90
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  • Piracetam Hydrazide - Nootropic Research

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  • Isoxazole-9 (ISX-9) is a neurogenic agent that promotes neurogenesis in vivo through the mechanisms of enhancing the proliferation and differentiation of hippocampal subgranular zone neuroblasts with resultant effects upon enhancing memory and potential antidepressant effects. Indications for neurogenic and antidepressant research.

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  • β-ANDROSTENETRIOL-OA (TLR-108) is an optimized analogue intended for research into optimization of agents toward the goal of an optimized adjunct agent to foster anxiolysis, cortisol reduction, and reduction of stress induced symptomatologies devoid of any adverse effects.  Indicated for anxiolytic/stress and anti-obesity research.

    $69.95
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  • Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies.  Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances.   Guanfacine promotes increased secretion of growth hormone.

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  • Rasagiline is a novel, highly potent, irreversible monamine oxidase B inhibitor (selective), which is related to Selegiline.  It has also been observed to exhibit neuroprotective, neurotrophic, and mitochondriaprotective actions.  Rasagiline demonstrates an ability to promote increased levels of NGF, GDNF. and BDNF proteins and expression.

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  • Optimized Extract - Analgesic Optimization Research Scientifically Engineered Selective Opioid Receptor Modulation Extract designed and developed for optimized analgesia with superior therapeutic index with markedly lower tolerance and adverse effects as classical opiate analgesics. Research Indications: Analgesic, Antidepressant, Anxiolytic research

    $39.95
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  • Roflumilast is a potent, long-acting, selective PDE4 Inhibitor (PDE4i) displaying anti-inflammatory and cognitive enhancing/nootropic properties.   Indications exist for research that applies to many psychoneurodysfunctional conditions as well as nootropic, ADHD/focus, and anti-inflammatory research.

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  • Optimized Extract - Addiction Cessation Research Scientifically Engineered Proprietary Optimized Extract Formulation Acting Upon Resetting Addiction Targeted Pathways and Counteracting Hyper-Psychoneurodysfunctional States. Indication for anti-addiction, anti-withdrawal, antidepressant, anxiolytic, neurogenic, anti-obesity, mood disorder treatment, and...

    $189.95
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    Optimized Extract - Optimized Libidogenic Research Scientifically Engineered Selective Melanocortin-4 Receptor (MC4R) Activator Extract Indicated for libido depression, erectile dysfunction, pro-sexual functionality research

    $48.30 $69.00 -30%
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    Optimized Extract - Anxiolytic Nootropic Research SGAN-OX Scientifically Engineered Sceletium Anxiolytic Nootropic Extract Indications for anxiolytic, nootropic, anti-inflammatory research.

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    $49.77 $71.10 -30%

    SBZD-OX Guided Scientifically Engineered Selective BZD Modulator Extract Indications for anxiolytic research.

    $49.77 $71.10 -30%
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  • Emoxypine (a.k.a. Mexidol, Mexifin - specifically within its succinate salt form), is an unusually pleiotropic anti-oxidant with structural resemblance to pyridoxine with several research indications.  Indications include anxiolytic, nootropic, neuroprotective, antidepressant, anti-hypoxic, and anti-addictive research.

    $24.95
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  • Mitoquinone (MitoQ) is a derivative of CoQ10 based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria, the organelles inside cells that provide energy for life processes, where they accumulate up to a thousand fold.

    $139.95
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  • SkQ1 CAS# 934826-68-3 (plastoquinonyl decyltriphenyl phosphonium, PDTP) SKQ1 is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS)

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  • Ibudilast has bronchodilator, vasodilator, anti-inflammatory, analgesic, anti-addiction, nootropic and neuroprotective effects. Used in the treatment of asthma and stroke. Indication show potential to treat MS, ALS, pain, and addiction. Ibudilast crosses the blood–brain barrier and suppresses glial cell activation. Research: Nootropic, Neuroprotection,...

    $149.95
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  • Longevitide™-OA  This peptide, newly developed and created by TeamTLR Science, is the state of the art in overall 'core' anti-aging, neuroprotection, and overall regeneration and enhancement.

    $595.00
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  • DONA-OX: Dual Opioidergic Novel Analgesic Optimized Xtract Scientifically Engineered, Wholly Novel, Herbal-Based Extract Matrix researched and developed by TeamTLR Science is a unique “dual opioidergic” activating extract with solid functional agonist bias at the MOR and OLR-1r receptors for enhanced analgesic efficacy. Research Indications: Analgesia,...

    $49.95
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  • SCAX-OX: Super Clean Anxiolytic Optimized Xtract Scientifically Engineered, Wholly Novel, Herbal-Based Extract Matrix researched and developed by TeamTLR Science is a unique BDZ-site activating extract that has optimum functional positive allosteric modulating (PAM) bias at the key ‘pure anxiolytic’ BZD receptors. Research Indications:...

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  • SCAD-OX:  Super Clean Antidepressant Optimized Xtract Scientifically Engineered, Wholly Novel, Herbal-Based Extract Matrix researched and developed by TeamTLR Science with unique glutamatergic activating extract that has optimum functional positive allosteric modulating bias at key AMPA glutamatergic receptors. Research Indications: Depression, Bipolar...

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  • Metformin HCl is marketed as a first-line medication for the treatment of type 2 diabetes.  It has recently been shown to possess significant anti-aging properties and such research is now being furthered for this direction. Research Indications: Anti-Aging, Diabetes

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  • Rapamycin CAS#  53123-88-9

    $198.95
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  • Zolmitriptan CAS# 139264-17-8 is a potent 5-HT1B/1D/1F agonist (Ki values are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1B and h5-HT1Freceptors respectively).   Primary medical usage is to treat migraines

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  • Haloperidol marketed under the trade name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, nausea and vomiting, delirium, agitation, acute psychosis, and hallucinations in alcohol withdrawal.

    $59.95
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  • Tropisetron HCl Tropisetron HCl is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.

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  • Lubiprostone (Amitiza, RU-0211, SPI-0211) Lubiprostone is a bicyclic aftty acid derived from PGE1  that acts by specifically activating CIC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. Lubiprostone is used for the treatment of chronic constipation of unknown cause in adults, as...

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    NRTB-OX Proprietary Optimized NR2B[NMDA complex] inhibiting modulator Xtract the possesses a unique ability to cleanly modulate the NRB2[NMDA] complex in a synergistic manner that appears worthy of further research exploration within both antidepressant and analgesic paradigms. Research Indications:  Antidepressant, Analgesic

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  • Recombinant Human Deoxyribonuclease 1 [rhDNase1] Alzheimer's Research, Cystic Fibrosis Research Recent studies indicate a high degree of effectiveness of rhDNase1 within alleviating the symptoms of conditions such as Alzheimer's and Cystic Fibrosis.

    $2,595.00
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  • Restoratide-OA is a proprietary peptide developed by TeamTLR that displays high potency and efficacy in a broad range of paradigms with restorative/corrective and enhancing properties. Positive corrective modulation of sex hormones, HPTA functionality, and glucocorticoidergic tone.  Research Indications: Anti-aging, neurogenic, analgesic, anti-addiction,...

    $359.96 $399.95 -10%
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  • Betahistine HCl 99% H1 agonist and high affinity H3 inverse agonist/antagonist. Research Indications:  Vigilance Research

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    DARI-OX is a scientifically engineered proprietary Optimized Dopamine Reuptake Inhibitor Xtract with high selectivity for the dopamine transporter (DAT) and a ratio of selectivity to noradrenaline (NET) and serotonin transporters (SERT) very similar to classical DARI reference standards. Research Indications: Vigilance/Focus, ADHD, Parkinson's

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  • Nilotinib 99% CAS 641571-10-0  is a selective Bcr/Abl tyrosine kinase inhibitor currently in use as an anti-cancer agent, that as well shows promise in alleviating conditions such as Parkinson's Disease and Alzheimer's Disease. Research Indications:  Anti-Cancer, Parkinson's, Alzheimer's

    $499.95
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    ORPA-ULTRA is a refined variation on th ORPA-OX platform to create a stronger Optimized Xtract with similar qualities.  ORPA-ULTRA is a moderate partial agonist at the MOR and DOR that demonstrates a clean efficacy free from adverse effects, tolerance, and addiction potential. Research Indications:  Analgesia, Opioidergic, Antidepressant/Mood Elevation,...

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  • SORM-ULTRAMEGA (SUM) proprietary scientifically engineered Optimized Xtract is a functionally selective MOR and DOR dual agonist with superior efficacy against complex pain and anxiety-related conditions. It engenders a superior overall tone of therapeutic efficacy with diminished tolerance potential than classical opiates. Research Indications: Analgesic...

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  • Thymosin Beta-4 (aka TB-500) 10mg vials lyophilized powder Thymosin Beta-4 (aka TB-500) is a code for a synthesized protein TMSB4X that is encoded in the human gene code. This protein is made up of 43 amino acids that help to encode actin sequestering proteins that play a role in cell differentiation, proliferation and migration. Research Indications:...

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  • Edaravone is a compound that possesses nootropic and neuroprotective properties, primarily to date used in the recovery of neurological function following acute ischemia. By acting as a potent antioxidant it strongly scavenges free radicals, protects against oxidative stress and neural apoptosis. Research Indications: Anti-Aging Research, Nootropic...

    $49.95
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  • C60 Fullerene 99.95% Ultra-Pure Anti-aging Research

    $99.95
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    ANXIOLYZE-OX aka ANXI-OX is a groundbreaking, revolutionary research matrix of natural agents intended for intranasal research to assess and promote the in vivo effects of potent, rapid-onset anxiolysis and pro-social behaviors. Research Indications: Anxiolytic Research

    $69.97 $99.95 -30%
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  • DIHEXA 99% Limited Run of highest quality standard DIHEXA 99% Research Indications:  Neurogenic, Nootropic, Antidepressant, Vigilance/Focus

    $199.95
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  • Flibanserin is a 5-HT1A receptor agonist and 5-HT2A receptor antagonist. Flibanserin has high affinity for human 5-HT1A receptors (Ki = 1 nm) and lower affinity for 5-HT2A (Ki = 49 nm) and D4 (Ki = 4–24 nm) receptors. Research Indications: Libidogenic/Sex Research, Antidepressant Research, Anxiolytic Research, Serotonergic Research

    $59.95
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  • Rosmarinic acid has antioxidant, anti-inflammatory (ie., artherosclerosis, rheumatoid arthritis),anti-allergenic (ie., allergic asthma) and antimicrobial activities. Through inhibition of indoleamine-2,3-dioxygenase (IDO) RA may as well have notable affects on cognition, focus, mood, especially as it may be able to exert remediation of "brain fog" and...

    $34.95
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  • Etizolam 99% CAS# 40054-69-1 Etizolam is a thienotriazolodiazepine which has an anxiolyticanxiolytic action about 6 times greater than that of diazaepam.Etizolam produces, especially at higher dosages, a reduction in time taken to fall asleep, an increase in total sleep time, and a reduction in the number of awakenings. Research Indications: Anxiolytic...

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    COPE-OX Optimized Clean Opioid Xtract is a proprietary, novel extract that modulates the opioid system for optimized analgesic and mood-elevating benefits largely sans the typical adverse effects associated with opioids. Research Indications:  Analgesia Research, Antidepressant Research, Anxiolytic Research

    $48.97 $69.95 -30%
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    $59.85 $85.50 -30%
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    HEBM-OX High Efficacy Benzodiazepine Modulator - Optimized Xtract is perhaps to date the cleanest anxiolytic benzodiazepine-site positive modulator with a high degree of potency, selectivity, and efficacy.  Minimized adverse effect potential with robust anxiolysis creates a near perfect benzodiazepine-site modulator for clean anxiolytic efficacy. Research...

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  • Glutamatergic NMDA receptor antagonist

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  • Tianeptine is a full agonist at the at the μ  and δ opioid receptors with negligible effect at the κ opioid receptors. Research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e.,AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

    $49.95
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  • Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications:  Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research

    $19.90
    In stock
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    $39.83 $56.90 -30%

    Optimized Extract – Mood Elevation Optimization Research -- Indications for analgesic, antidepressant (mood elevation), anxiolytic (SAD) research

    $39.83 $56.90 -30%
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  • J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...

    $99.95
    In stock
  • Etizolam 99% CAS# 40054-69-1 Etizolam is a thienotriazolodiazepine which has an anxiolyticanxiolytic action about 6 times greater than that of diazaepam.Etizolam produces, especially at higher dosages, a reduction in time taken to fall asleep, an increase in total sleep time, and a reduction in the number of awakenings. Research Indications: Anxiolytic...

    $149.95
    In stock
  • 9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications:  Dopaminergic Research, Addiction Research, Neuroprotection Research

    $99.95
    In stock
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    $69.93 $99.90 -30%

    Optimized Analogue - Eugeroic Nootropic Research *** EUGERAFINIL-OA (TLR-203) is a TLR-OA compound intended for research into optimization of agents toward the goal of an optimized eugeroic to best foster the promotion of effects that include enhanced vigilance, wakefulness, energy, and focus.

    $69.93 $99.90 -30%
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  • SENOLYTIXTM is an optimized combination of Dasatinib(D) and Quercetin(Q) based off the landmark science into practically applicable senolytics. SENOLYTIXTM offers the most optimized formulation for progressive research into the paradigm of senolytic agents to date and to afford progress within research against the ravages of aging. Research Indications:...

    $119.95
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  • Emoxypine (a.k.a. Mexidol, Mexifin - specifically within its succinate salt form), is an unusually pleiotropic anti-oxidant with structural resemblance to pyridoxine with several research indications.  Indications include anxiolytic, nootropic, neuroprotective, antidepressant, anti-hypoxic, and anti-addictive research.

    $24.95
    In stock