Zolmitriptan CAS 139264-17-8

Zolmitriptan CAS# 139264-17-8 is a potent 5-HT_1B/1D/1F agonist (K_i values are 0.63, 5.01 and 63.09 nM for h5-HT_1D, h5-HT_1B and h5-HT_1Freceptors respectively), as well as an activator of SR-1B.

Primary medical usage is to treat migraines.  It is a triptan, used in the acute treatment of migraine attacks with or without aura and cluster headaches.

Zolmitriptan is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine.

Zolmitriptan is available as a swallowable tablet, an oral disintegrating tablet, and a nasal spray, in doses of 2.5 and 5 mg.

Chemical Name: (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone

CAS#: 139264-17-8

M.Wt:287.36

Formula:C₁₆H₂₁N₃O₂

Solubility:Soluble to 100 mM in DMSO and to 100 mM in ethanol

USAGE: For Research Use Only! Not For Use in Humans.