Tianeptine is a full agonist at the at the μ and δ opioid receptors with negligible effect at the κ opioid receptors. Research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e.,AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Fasoracetam (a.k.a. NS-105 and LAM-105) is a potent HACU-inhibiting, cAMP-modulating, GABAB receptor upregulating/antagonizing, mGluR-modulating, non-monoaminergic anti-depressant nootropic. Research Indications: Nootropic, Antidepressant, Anxiolytic, ADHD Research, Addiction Cessation, GABAergics/Benzodiazepine Research
J147 has displayed neurotrophic, neuroprotective, neuroanti-inflammatory, nootropic and LTP-enhancing activity. It is a potent, orally active hybrid of curcumin and cyclohexyl-bisphenol A. J147 research demonstrates an ability to reduce soluble Aβ40 and Aβ42 levels. Indicated for neurogenic, antidepressant, anti-psychoneurodysfunctionality, anxiolytic...
9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
Optimized Analogue - Eugeroic Nootropic Research *** EUGERAFINIL-OA (TLR-203) is a TLR-OA compound intended for research into optimization of agents toward the goal of an optimized eugeroic to best foster the promotion of effects that include enhanced vigilance, wakefulness, energy, and focus.
SENOLYTIXTM is an optimized combination of Dasatinib(D) and Quercetin(Q) based off the landmark science into practically applicable senolytics. SENOLYTIXTM offers the most optimized formulation for progressive research into the paradigm of senolytic agents to date and to afford progress within research against the ravages of aging. Research Indications:...
Emoxypine (a.k.a. Mexidol, Mexifin - specifically within its succinate salt form), is an unusually pleiotropic anti-oxidant with structural resemblance to pyridoxine with several research indications. Indications include anxiolytic, nootropic, neuroprotective, antidepressant, anti-hypoxic, and anti-addictive research.
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.
Optimized Extract - Addiction Cessation Research Scientifically Engineered Proprietary Optimized Extract Formulation Acting Upon Resetting Addiction Targeted Pathways and Counteracting Hyper-Psychoneurodysfunctional States. Indication for anti-addiction, anti-withdrawal, antidepressant, anxiolytic, neurogenic, anti-obesity, mood disorder treatment, and...
Rasagiline is a novel, highly potent, irreversible monamine oxidase B inhibitor (selective), which is related to Selegiline. It has also been observed to exhibit neuroprotective, neurotrophic, and mitochondriaprotective actions. Rasagiline demonstrates an ability to promote increased levels of NGF, GDNF. and BDNF proteins and expression.