Agents with a dominant or highly significant serotonergic pathway(s) modulating mechanism of action
Buspirone HCl is a classic 5-HT1A partial agonist with relatively high affinity (Ki = 9.3 - 29.5 nM). A clinically effective anxiolytic. Research Indications: Anxiolytic Research, Addiction Cessation (incl. Smoking/Nicotine) Research, Autism Research, Serotonergic Research
Ketanserin Tartrate is a potent and selective 5HT2A antagonist. It has demonstrated neurogenic, addiction cessation, sleep enhancement, anxiolytic, and anti=psychotic properties, among others Research Indications: Serotonergic research, Anxiolytic Research, Psychoneurodysfunctional Research, HPPD-related Research.
Zolmitriptan CAS# 139264-17-8 is a potent 5-HT1B/1D/1F agonist (Ki values are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1B and h5-HT1Freceptors respectively). Primary medical usage is to treat migraines
Tropisetron HCl Tropisetron HCl is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.
Optimized Extract - Anxiolytic Nootropic Research SGAN-OX Scientifically Engineered Sceletium Anxiolytic Nootropic Extract Indications for anxiolytic, nootropic, anti-inflammatory research.
Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18–64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. Research Indications: Libidogenic/Sex Research,...
Flibanserin is a 5-HT1A receptor agonist and 5-HT2A receptor antagonist. Flibanserin has high affinity for human 5-HT1A receptors (Ki = 1 nm) and lower affinity for 5-HT2A (Ki = 49 nm) and D4 (Ki = 4–24 nm) receptors. Research Indications: Libidogenic/Sex Research, Antidepressant Research, Anxiolytic Research, Serotonergic Research