Agents with a dominant or highly significant opioidergic pathway(s) modulating mechanism of action
OPIO-OX Opioid System Enhancer Optimized Xtract Formulation Targets multiple opioidergic pathways to optimize the opioidergic system for enhanced beneficial effects within goals of analgesic-sparing, tolerance sparing, and adverse effects sparing outcomes. Research Indications: Opioidergic Research, Analgesia Research, Addiction Research
ORPA-ULTRA is a refined variation on th ORPA-OX platform to create a stronger Optimized Xtract with similar qualities. ORPA-ULTRA is a moderate partial agonist at the MOR and DOR that demonstrates a clean efficacy free from adverse effects, tolerance, and addiction potential. Research Indications: Analgesia, Opioidergic, Antidepressant/Mood Elevation,...
ENKI-OX Scientifically Engineered Enkephalinase Inhibitor -- Indications for analgesia, antidepressant, anxiolytic research, and anti-addiction research.
Optimized Extract - Analgesic Optimization Research Scientifically Engineered Selective Opioid Receptor Modulation Extract designed and developed for optimized analgesia with superior therapeutic index with markedly lower tolerance and adverse effects as classical opiate analgesics. Research Indications: Analgesic, Antidepressant, Anxiolytic research
DONA-OX: Dual Opioidergic Novel Analgesic Optimized Xtract Scientifically Engineered, Wholly Novel, Herbal-Based Extract Matrix researched and developed by TeamTLR Science is a unique “dual opioidergic” activating extract with solid functional agonist bias at the MOR and OLR-1r receptors for enhanced analgesic efficacy. Research Indications:...
SFME-OX Selective Filamin A MOR-System Enhancer Optimized Xtract binds Filamin A in a highly selective manner that demonstrates the effect of markedly reversing and reducing Mu-Opioid Receptor System (MOR-S) tolerance. Research Indications: Analgesia Research, Addiction Research, Opioidergic Research, Anti-Inflammatory Research.
Restoratide-OA is a proprietary peptide developed by TeamTLR that displays high potency and efficacy in a broad range of paradigms with restorative/corrective and enhancing properties. Positive corrective modulation of sex hormones, HPTA functionality, and glucocorticoidergic tone. Research Indications: Anti-aging, neurogenic, analgesic, anti-addiction,...
SOMA-OX is a proprietary herbal extract derived from Stephania genus optimized to foster modulation of pathways that promote analgesic-sparing, tolerance sparing, and adverse effects sparing outcomes within pain management protocols. Potentials for strong efficacy in addiction cessation. Research Indications: Analgesic Research, Addiction...
Tianeptine Sulfate (Tianeptine Hemisulfate Monosodium Salt) is a novel pseudo-analogue of Tianeptine wherein the substituted hemisulfate monosodium salt creates a duration of in vivo activity that far exceeds that of the parent as well as the prior commercially available existing sodium salt form. Research Indications: Antidepressant Research,...
KORX-OX - Kappa Opioid Receptor Antagonist Optimized Xtract First-In-Class orally bioavailable, long-acting kappa-opioid receptor (KOR) antagonist herbal extract. Activates the c-Jun pathway to 'corrupt' the KOR akin to that of the class of synthetic KOR antagonists. Research Indications: Opioidergic Research, Antidepressant Research, Anxiolytic...
Enkephinex-OA is an enkephalinase inhibitor with modest oral potency and efficacious BBB penetration. An analogue of RB-120 it demonstrates robust efficacy within in vivo models for analgesic, antidepressant, and anxiolytic paradigms. Research Indications: Analgesic Research, Anti-Addiction Research, Antidepressant Research, Anxiolytic Research.
COPE-OX Optimized Clean Opioid Xtract is a proprietary, novel extract that modulates the opioid system for optimized analgesic and mood-elevating benefits largely sans the typical adverse effects associated with opioids. Research Indications: Analgesia Research, Antidepressant Research, Anxiolytic Research