All synthetic chemicals available for research that demonstrate an effect on neuropsychochemistry
Agomelatine is a melatonergic agonist promoting fairly rapid acting antidepressant effects. It is particularly effective within paradigms of poor sleep quality and circadian rhythm dysregulation; benefit to anxiolytic and stress-response tone. Indications for antidepressant (MDD), anxiolytic, and somnolescent research, as well as potential indications...
Rimonabant is a potent CB1R inverse agonist demonstrating significant anti-obesity and anti-addiction effects, as well as calorie restriction mimetic (CRM) anti-aging capacities. Research Indications: Anti-obesity, Anti-aging, and Anti-addiction (smoking cessation, et al.) research.
URB597 is a potent, orally bioavailable FAAH inhibitor. URB597 inhibits hydrolysis of FAAH metabolized substrates within the endocannabinoid and related systems invoking a parallel increase in brain anandamide, OEA, and PEA. Efficacy on parameters of mood, anxiety, and analgesia with no demonstration of adverse effects.
9-Methyl-9B-Carboline is a dopaminergic enhancer that up-regulates, differentiates and protects dopaminergic neurons, dendrities and synapses, especially in the substantia nigra of the midbrain and in the hippocampus, as well as enhances dopamine synthesis. Research Indications: Dopaminergic Research, Addiction Research, Neuroprotection Research
Optimized Analogue - Eugeroic Nootropic Research *** EUGERAFINIL-OA (TLR-203) is a TLR-OA compound intended for research into optimization of agents toward the goal of an optimized eugeroic to best foster the promotion of effects that include enhanced vigilance, wakefulness, energy, and focus.
Enkephinex-OA is an enkephalinase inhibitor with modest oral potency and efficacious BBB penetration. An analogue of RB-120 it demonstrates robust efficacy within in vivo models for analgesic, antidepressant, and anxiolytic paradigms. Research Indications: Analgesic Research, Anti-Addiction Research, Antidepressant Research, Anxiolytic Research.
Flumazenil is a potent benzodiazepine receptor antagonist. Flumazenil administration has been demonstrated to have efficacy to reverse benzodiazepine tolerance and create a facilitation of rapidly alleviating PAWS (Post-Acute Withdrawal Syndrome). Research Indications: Addiction Research, GABAergic/Benzodiazepine Research, Anxiolytic Research
Guanfacine is a nootropic, sympatholytic, α2A receptor agonist that has been indicated for ADHD and OCD symptomatologies. Guanfacine as well has demonstrated an indication for reduction of opioid withdrawals and detoxification of recreational substances. Guanfacine promotes increased secretion of growth hormone.
NRX-1074 is an NMDA Glycine-Site Functional Weak Partial Agonist with potent efficacy demonstrated for treatment of depression. It as well has neurogenic/synaptogenic and nootropic/cognitive enhancing properties. Research Indications: Antidepressant, Neurogenic, Nootropic Research
Tianeptine Sulfate (Tianeptine Hemisulfate Monosodium Salt) is a novel pseudo-analogue of Tianeptine wherein the substituted hemisulfate monosodium salt creates a duration of in vivo activity that far exceeds that of the parent as well as the prior commercially available existing sodium salt form. Research Indications: Antidepressant Research,...